An Archives of Physical Medicine and Rehabilitation trial shows community exercise prescribed by spinal cord injury guidelines significantly reduces chronic pain intensity.
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Non-Canonical ISGylation Pathway Restricts Respiratory Syncytial Virus Infection in Epithelial Cells
A Cell Communication and Signaling study demonstrates that extracellular ISG15 triggers an interferon-independent integrin-FAK signaling pathway to restrict viral infections in epithelial cells.
Leading LLMs Demonstrate High Diagnostic Safety and Low Overuse in Choosing Wisely Scenarios
An Annals of Internal Medicine study reveals large language models effectively identify low-value care, recommending unneeded tests in only 5.4% of cases.
Randomized Clinical Trial Evaluates Revascularization vs Medical Therapy for Carotid Cognitive Impairment
A JAMA study demonstrates that carotid revascularization does not improve cognitive outcomes compared to intensive medical management in asymptomatic severe carotid stenosis.
Identification of Low-Mortality/High-Decline Risk Phenotypes in Heart Failure via Machine Learning
A Journal of Cardiac Failure study shows XGBoost machine learning using discharge physical performance measures predicts one-year functional decline in older heart failure patients.