A Nature study reveals that human embryos efficiently repair base editor single-strand DNA damage, though off-target mosaicism currently prevents clinical germline application.
Most Recent Articles
Evaluating Antiseizure Medication Selection and Cardiovascular Outcomes During DOAC Therapy
A JAMA Neurology study demonstrates that concomitant levetiracetam and DOAC therapy in adults with epilepsy is associated with nearly double the risk of thromboembolic events and higher mortality.
Neurological and Systemic Complications of Varicella Zoster Virus Reactivation: A Comprehensive Review
A Nature Reviews Disease Primers study highlights that latent varicella zoster virus reactivation can drive severe stroke and neurovascular disease without causing a shingles rash.
Targeting EFHD1 Calcium-Dependent Organellar Contact Stabilization to Prevent Hepatic Injury
Inhibiting the EFHD1 protein reduces liver inflammation and scarring by up to 60% by blocking a maladaptive antiviral stress response in MASH.
Gut-Liver Axis Metabolomics Link Microbial Imidazole Propionate to Reduced Survival in PSC
A Nature Metabolism study reveals that gut bacterial imidazole propionate drives primary sclerosing cholangitis via mTORC1 signaling, opening new therapeutic avenues.