A Science Translational Medicine study shows molecular glue RPT04402 restores PP2A trimer assembly to drive tumor regression in high-grade uterine cancer.
Most Recent Articles
Abdominal Obesity Outperforms BMI Category in Predicting Early-Onset Malignancies in Young Adult Cohort
An Annals of Internal Medicine study of 6.3 million adults links young-adult obesity and central adiposity directly to increased early-onset cancer risk.
Lancet Oncology Study Highlights Alternating TKI and Monoclonal Antibody Regimen for Untreated Clear Cell RCC
A Lancet Oncology phase 1/2 trial shows alternating pazopanib and bevacizumab extends median overall survival to 63.2 months in metastatic clear cell renal cell carcinoma.
Symptom-Level Network Clustering Outperforms Traditional Diagnostic Labels in Predicting Therapy Outcomes
A Psychological Medicine network analysis of 33,675 patients reveals symptom-level clusters predict distinct 12-week psychotherapy trajectories in anxiety and depression.
Surface Plasmon Resonance Reveals Nanomolar Affinity and Six Heme-Binding Motifs on Plasmin
An International Journal of Biological Macromolecules study reveals that labile heme binds plasmin with nanomolar affinity, inhibiting fibrinolysis and linking hemolysis to thrombosis.