Nature Structural and Molecular Biology study identifies HERC4 as the molecular switch converting RIPK1 to initiate TNF-induced cell death.
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Vanderbilt Health researchers isolate human monoclonal antibodies that potently neutralize measles virus replication in preclinical models.
Concordance Analysis of Minigene Assays and Patient RNA Informs Clinical Splicing Guidelines
Genome Medicine study establishes clinical recommendations for using construct-based RNA splicing assays to resolve uncertain genetic variants in inherited diseases
Simultaneous Multi-Receptor Adenosine Antagonism Reduces Scar Formation in Human Heart Models
Stanford researchers uncover a shared adenosine receptor signaling pathway that drives cardiac fibrosis and offer a novel target for anti-fibrotic therapies.