A Nature Reviews Disease Primers study highlights that latent varicella zoster virus reactivation can drive severe stroke and neurovascular disease without causing a shingles rash.
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Targeting EFHD1 Calcium-Dependent Organellar Contact Stabilization to Prevent Hepatic Injury
Inhibiting the EFHD1 protein reduces liver inflammation and scarring by up to 60% by blocking a maladaptive antiviral stress response in MASH.
Gut-Liver Axis Metabolomics Link Microbial Imidazole Propionate to Reduced Survival in PSC
A Nature Metabolism study reveals that gut bacterial imidazole propionate drives primary sclerosing cholangitis via mTORC1 signaling, opening new therapeutic avenues.
Generative AI Integration in Cancer Care: Mapping Applications and Patient Perspectives
A scoping review in the European Journal of Cancer reveals key evidence gaps in patient perspectives regarding generative AI safety, equity, and governance in oncology.
Subclinical Leaflet Thrombosis Reductions With NOAC Monotherapy Following TAVI Procedures
The ACASA-TAVI trial published in JAMA shows NOAC monotherapy significantly reduces post-TAVI bioprosthetic leaflet thrombosis without increasing bleeding risks compared to aspirin.
