Salk Institute researchers revealed that mitochondrial citrate acts as a second messenger in mitohormetic signaling, protecting the adult heart against doxorubicin toxicity.
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Clopidogrel Monotherapy Versus Extended DAPT in High-Ischemic-Risk Stent Patients: The A-CLOSE Trial
The A-CLOSE trial published in NEJM shows extended DAPT reduces major ischemic events, whereas clopidogrel monotherapy lowers bleeding in high-risk post-stent patients.
Molecular Mechanisms of Sympathetic Circadian IOP Regulation in the Trabecular Meshwork
Kyushu University researchers revealed that norepinephrine elevates nighttime intraocular pressure by upregulating RHOB in the trabecular meshwork, opening new avenues for glaucoma chronotherapy.
Replacing Invasive Bone Marrow Sampling With FDG-PET in Pediatric Rhabdomyosarcoma Staging
A landmark Journal of Clinical Oncology study shows FDG-PET imaging can reliably replace painful bone marrow biopsies for staging pediatric rhabdomyosarcoma.
Cross-Disciplinary Frameworks for GLP-1 Prescribing in Patients With Co-Occurring Eating Disorders
Adelaide University researchers highlight the necessity of integrated multidisciplinary care as GLP-1 medicines bridge the divide between obesity and eating disorder treatment.