A preclinical study demonstrates that oral arginine administration suppresses amyloid β aggregation and alleviates neuroinflammation in animal models of Alzheimer's disease.
Most Recent Articles
Noninvasive Nasal Delivery of STING Agonists for Aggressive Brain Tumor Treatment
A new intranasal nanomedicine utilizing spherical nucleic acids successfully activates the cGAS-STING pathway to inhibit glioblastoma growth and enhance checkpoint inhibitor efficacy.
Evaluation of Intensive Medical Therapy Alone versus Revascularization for Carotid Stenosis
The CREST-2 trial demonstrates that carotid stenting, unlike endarterectomy, significantly lowers stroke risk in patients with asymptomatic high-grade stenosis when added to intensive medical therapy.
Dose-Response Relationship of Early Systolic Pressure to Later Arterial Plaque
New findings demonstrate that elevated adolescent blood pressure significantly increases the risk of severe coronary atherosclerosis in middle age, challenging current screening timelines.
Preclinical Evaluation of CAR Treg Therapy for Targeted Immunosuppression in Atherosclerosis
Preclinical data indicates that anti-OxLDL CAR regulatory T cells can reduce atherosclerotic plaque burden by approximately 70% through targeted local immunosuppression.