A new intranasal nanomedicine utilizing spherical nucleic acids successfully activates the cGAS-STING pathway to inhibit glioblastoma growth and enhance checkpoint inhibitor efficacy.
Most Recent Articles
Evaluation of Intensive Medical Therapy Alone versus Revascularization for Carotid Stenosis
The CREST-2 trial demonstrates that carotid stenting, unlike endarterectomy, significantly lowers stroke risk in patients with asymptomatic high-grade stenosis when added to intensive medical therapy.
Dose-Response Relationship of Early Systolic Pressure to Later Arterial Plaque
New findings demonstrate that elevated adolescent blood pressure significantly increases the risk of severe coronary atherosclerosis in middle age, challenging current screening timelines.
Preclinical Evaluation of CAR Treg Therapy for Targeted Immunosuppression in Atherosclerosis
Preclinical data indicates that anti-OxLDL CAR regulatory T cells can reduce atherosclerotic plaque burden by approximately 70% through targeted local immunosuppression.
AR Medium Facilitates Generation of Functional Cardiomyocytes from Canine iPSCs
Researchers have developed a novel culture medium that stabilizes canine induced pluripotent stem cells and directs their differentiation into functional, contracting cardiomyocytes for translational disease modeling.