A novel omics study identifies specific preoperative plasma metabolites and proteins that significantly improve the prediction of long-term blood pressure reduction in adolescents following bariatric surgery.
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Re-evaluating Age Stratification in AML: Evidence from Molecular and Clinical Data
A multi-dimensional analysis of adult AML reveals linear worsening of outcomes with age and no clear age cut-off, advocating for flexible drug approval and trial eligibility.
DMEK Graft Success Unaffected by Donor Diabetes: A Multicenter Study
A major clinical trial reveals no significant difference in 1-year DMEK graft success rates between diabetic and non-diabetic corneal donors, supporting an expanded donor pool.
STELLAR-303 Trial: Redefining Treatment for Refractory Metastatic Colorectal Cancer
The STELLAR-303 trial shows zanzalintinib plus atezolizumab significantly improves overall survival in refractory metastatic colorectal cancer, offering a new immunotherapy-based treatment option.
Personalizing Colon Cancer Treatment: The Role of Circulating Tumor DNA
The DYNAMIC-III trial reveals how ctDNA-guided adjuvant therapy impacts recurrence-free survival and treatment toxicity in stage III colon cancer, highlighting future challenges.
