A BMJ study identifies 24 common prescribing cascades where drug side effects are misdiagnosed, leading to unnecessary secondary prescriptions in older adults.
Most Recent Articles
Mechanistic Insights Into Statin Chemoprevention Against MASLD-Associated Hepatocellular Carcinoma
A Hepatology Communications study reveals that statins inhibit YAP signaling in hepatic stellate cells by lowering GGPP, explaining potential chemopreventive effects against MASLD-related liver cancer.
Protein Delivery of ABE8e-V106W Base Editors Supports Human Embryo Viability
A Nature study reveals that human embryos efficiently repair base editor single-strand DNA damage, though off-target mosaicism currently prevents clinical germline application.
Evaluating Antiseizure Medication Selection and Cardiovascular Outcomes During DOAC Therapy
A JAMA Neurology study demonstrates that concomitant levetiracetam and DOAC therapy in adults with epilepsy is associated with nearly double the risk of thromboembolic events and higher mortality.
Mitigating Reperfusion Injury and Infarct Size With Dexrazoxane in Acute STEMI
The SHIELD-MI trial demonstrates that peri-procedural intravenous dexrazoxane reduces intramyocardial hemorrhage by 68% and decreases infarct size in acute STEMI patients.