A novel human iPSC-derived heart tissue model replicates HFpEF diastolic dysfunction and reveals how SGLT2 inhibitors reduce cardiac inflammation through endothelial pathways.
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Targeting EFHD1 Calcium-Dependent Organellar Contact Stabilization to Prevent Hepatic Injury
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Gut-Liver Axis Metabolomics Link Microbial Imidazole Propionate to Reduced Survival in PSC
A Nature Metabolism study reveals that gut bacterial imidazole propionate drives primary sclerosing cholangitis via mTORC1 signaling, opening new therapeutic avenues.
