Cardiology Research

Unveiling Sudden Cardiac Arrest Risk Factors Among Hispanic and Latino Adults

Article Impact Level: HIGH
Data Quality: STRONG
Summary of Journal of the American Heart Association, 12(20), e030062. https://doi.org/10.1161/JAHA.123.030062
Dr. Kyndaron Reinier et al.

Points

  • Out-of-hospital sudden cardiac arrest (SCA) is a significant cause of mortality, and there is a lack of research on SCA risk among Hispanic and Latino individuals in the United States.
  • The study analyzed data from the Ventura Prediction of Sudden Death in Multi-Ethnic Communities (PRESTO) study and the Hispanic Community Health Survey/Study of Latinos (HCHS/SOL), involving 1,468 SCA cases and 3,033 control subjects.
  • Clinical variables associated with an increased risk of SCA in Hispanic or Latino individuals included chronic kidney disease, heavy drinking, stroke, atrial fibrillation, coronary artery disease, heart failure, and diabetes.
  • Chronic kidney disease emerged as the most significant risk factor for SCA, with an odds ratio of 7.3, emphasizing its importance in SCA risk assessment.
  • The study suggests that early identification and management of chronic kidney disease and prevention and treatment of cardiovascular disease are crucial in reducing the risk of SCA among Hispanic and Latino individuals.

Summary

A recent research paper focuses on the critical issue of out-of-hospital sudden cardiac arrest (SCA), a leading cause of mortality, particularly among the Hispanic and Latino population in the United States. The study, conducted as a case-control investigation, analyzed data from the Ventura Prediction of Sudden Death in Multi-Ethnic Communities (PRESTO) study from 2015 to 2021. The research included 1,468 adult SCA cases aged 18 to 85. At the same time, control subjects were drawn from 3,033 Hispanic or Latino participants who underwent Visit 2 examinations between 2014 and 2017 in the San Diego site of the Hispanic Community Health Survey/Study of Latinos (HCHS/SOL). The results, accounting for age, gender, and various clinical factors, unveiled several significant associations between specific health conditions and the risk of SCA among Hispanic or Latino individuals.

The study’s findings highlight the specific clinical variables linked to an increased risk of SCA within the Hispanic or Latino population. Notably, chronic kidney disease emerged as the most potent risk factor for SCA, with an odds ratio of 7.3 (95% CI, 3.8-14.3). Other factors significantly associated with SCA risk included heavy drinking (OR 4.5), stroke (OR 3.1), atrial fibrillation (OR 3.7), coronary artery disease (OR 2.9), heart failure (OR 2.5), and diabetes (OR 1.5). These results emphasize the importance of early identification and management of chronic kidney disease and the critical role of addressing cardiovascular disease in reducing the risk of SCA among Hispanic and Latino individuals.

In conclusion, this study represents the first population-based investigation regarding SCA risk predictors among Hispanic or Latino adults. The research underscores the imperative need to address chronic kidney disease and cardiovascular disease as central components of SCA prevention and management strategies within this demographic. Public health initiatives can significantly reduce SCA-related mortality within the Hispanic and Latino communities in the United States by targeting these risk factors.

Link to the article: https://onlinelibrary.wiley.com/doi/10.1002/clc.24076

References

Reinier, K., Moon, J., Chugh, H. S., Sargsyan, A., Nakamura, K., Norby, F. L., Uy‐Evanado, A., Talavera, G. A., Gallo, L. C., Daviglus, M. L., Hadduck, K., Shepherd, D., Salvucci, A., Kaplan, R. C., & Chugh, S. S. (2023). Risk factors for sudden cardiac arrest among hispanic or latino adults in southern california: Ventura presto and hchs/sol. Journal of the American Heart Association, 12(20), e030062. https://doi.org/10.1161/JAHA.123.030062

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