Article Impact Level: HIGH Data Quality: STRONG Summary of European Heart Journal, ehac378. https://doi.org/10.1093/eurheartj/ehac378 Dr. Ines Garcia-Lunar et al
Points
- The main purpose of the trial was to evaluate the effect of comprehensive lifestyle intervention on the risk of cardiovascular disease.
- The trial for comprehensive lifestyle intervention indicated the betterment in the risk score of cardiovascular disease at 1 year and dissolute at 3 years.
- This intervention benefits the low atherosclerosis burden group as compared to individuals having a high atherosclerosis burden.
Summary
Eligible asymptomatic individuals between the age range 40-50 years from the progression of early sub-clinical atherosclerosis cohort were selected through stratified randomization sample techniques in Spain. Stratification was based on baseline subclinical atherosclerosis (low = 720 and high = 300 atherosclerosis burden) which was detected in aortic, carotid, and iliofemoral arteries through vascular ultrasound and through the calcification of coronary artery with computed tomography.
A sample of 1020 individuals was selected and lifestyle intervention was provided based on the sit-stand workstation, physical activity tracker, and 12 individualized motivational sessions. Individuals who completed all baseline assessments were selected and those who have cancer, cardiovascular disease, or any other serious illness which shortens the lifespan were excluded. Persons having normal body index, no plaque burden, and a normal lifestyle were also excluded.
The result of the study shows that lifestyle intervention due to the prespecified adaptation of Fuster-BEWAT (BEWAT = Blood pressure, Exercise, Weight (BMI), Alimentation, and Tobacco) made improvements in cardiovascular risk score for 1 year and it decreases with the passage of time and lowers at 3 years. The study also indicated that this intervention benefits the individuals having low atherosclerosis burden and has no benefits for those having high atherosclerosis burden.
Link to the article: https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehac378/6649085
References Garcia-Lunar, I., van der Ploeg, H. P., Fernández Alvira, J. M., van Nassau, F., Castellano Vázquez, J. M., van der Beek, A. J., Rossello, X., Fernández-Ortiz, A., Coffeng, J., van Dongen, J. M., Mendiguren, J. M., Ibáñez, B., van Mechelen, W., & Fuster, V. (2022). Effects of a comprehensive lifestyle intervention on cardiovascular health: The TANSNIP-PESA trial. European Heart Journal, ehac378. https://doi.org/10.1093/eurheartj/ehac378
