Article Impact Level: HIGH Data Quality: STRONG Summary of Clinical Cardiology, 46(11), 1310–1318. https://doi.org/10.1002/clc.24110 Dr. Jie Hou et al.
Points
- The study aimed to evaluate the prognostic value of mitral annular calcification (MAC) scores derived from non-contrast cardiac computed tomography (CT) in patients with mitral valve disease (MVD).
- A total of 300 consecutive MVD patients were enrolled, with 80 having MAC-present and 220 having MAC-absent, revealing that MAC-present patients were older, predominantly female, and exhibited a higher prevalence of various cardiovascular conditions.
- MAC-present patients had a significantly higher rate of intraoperative conversion from mitral valve repair to replacement and experienced a greater incidence of arrhythmias during the follow-up period.
- Multiple logistic regression analyses identified MAC scores as an independent predictor of intraoperative conversion. In contrast, Cox regression analyses demonstrated the association of MAC scores and left atrial end-diastolic dimension (LADD) with follow-up arrhythmias.
- The findings highlight the clinical significance of MAC scores derived from non-contrast cardiac CT in MVD patients. They emphasize their association with intraoperative conversion and follow-up arrhythmias, offering potential implications for clinical decision-making and patient outcomes.
Summary
The research aimed to assess the prognostic value of mitral annular calcification (MAC) scores derived from non-contrast cardiac computed tomography (CT) in patients with mitral valve disease (MVD). Three hundred consecutive MVD patients, including 80 with MAC-present and 220 with MAC-absent, were prospectively enrolled between January 2020 and December 2021. The study revealed that MAC-present patients were older and predominantly female. It exhibited a higher prevalence of aortic valve calcification, mitral stenosis, atrial fibrillation, and larger left atrial end-diastolic dimension (LADD) than MAC-absent patients. Additionally, MAC-present patients had a significantly higher rate of intraoperative conversion from mitral valve repair to replacement and experienced a greater incidence of arrhythmias during the follow-up period. Multiple logistic regression analyses identified MAC scores as an independent predictor of intraoperative conversion, while Cox regression analyses demonstrated the association of MAC scores and LADD with follow-up arrhythmias.
The findings underscore the significant prognostic value of non-contrast cardiac CT-derived MAC scores in MVD patients, particularly in predicting the risk of intraoperative conversion and the occurrence of arrhythmias during follow-up. The study’s comprehensive analysis of baseline clinical data, intraoperative outcomes, and follow-up arrhythmia data provides valuable insights into the potential utility of quantitative MAC parameters for enhancing the management of MVD. These results contribute to the growing evidence supporting non-contrast cardiac CT-derived MAC scores as a valuable prognostic tool in MVD patient care, offering potential implications for clinical decision-making and patient outcomes.
The research highlights the clinical significance of MAC scores derived from non-contrast cardiac CT in MVD patients, emphasizing their association with intraoperative conversion and follow-up arrhythmias. These findings underscore the potential of MAC scores as an important prognostic indicator for risk assessment and management in MVD patients, thereby enhancing the understanding and treatment of this patient population.
Link to the article: https://onlinelibrary.wiley.com/doi/10.1002/clc.24110
References Hou, J., Sun, Y., Wang, H., Zhang, L., Shi, J., You, H., Zhang, R., & Yang, B. (2023). Noncontrast cardiac computed tomography-derived mitral annular calcification scores in mitral valve disease. Clinical Cardiology, 46(11), 1310–1318. https://doi.org/10.1002/clc.24110
