A new study reveals that beta arrestin 1 is essential for maintaining healthy blood pressure in the lungs by ensuring signaling molecules remain sensitive to nitric oxide.
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Transfemoral Management of Mechanical Aortic Valve Failure via Disk Fragmentation
Researchers have successfully performed the first percutaneous mechanical valve-in-valve procedures, allowing doctors to replace defective mechanical heart valves through a catheter instead of high-risk repeat open-heart surgery
Predictive Accuracy of the Goliat Model in Estimating 48-Hour TBI Complications
The newly validated Goliat score allows emergency clinicians to accurately predict 48-hour complications in patients with non-severe traumatic brain injury using clinical indicators and S100B protein levels.
Bioelectronic Modulation of IL-6 and Amyloid-Beta in Surgical Trauma
A minimally invasive bioelectronic device that stimulates the vagus nerve has been shown to reduce brain inflammation and amyloid protein buildup, potentially preventing permanent cognitive decline after surgery
A Next-Generation Platform for Predicting Human Immune Responses to IgG Antibodies
An international research team has developed a humanized mouse model that accurately replicates human immune receptor biology to better predict the safety and efficacy of antibody-based medicines.