New research reveals that the common diabetes drug metformin works through a previously unknown pathway in the brain, changing our understanding of how it controls blood sugar.
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Longitudinal MVPA Trajectories Reveal Pre-CVD Decline and Persistent Post-Event Deficits
A long-term study reveals that a decline in physical activity begins roughly 12 years before a person develops cardiovascular disease.
Age-Related Vascular Response to Dietary Nitrate Is Mediated by Oral Microbiome Modulation
In older adults, dietary nitrate supplementation lowers blood pressure by selectively suppressing specific harmful oral bacteria, an effect not observed in younger individuals.
Gut Metabolite Imidazole Propionate Identified as a Causal Agent in Atherosclerosis
New research reveals that a gut-derived metabolite is not only a marker but also a direct cause of atherosclerosis, opening up new avenues for diagnosis and treatment.
Cardiovascular Risk of Individual Sulfonylureas vs. DPP-4 Inhibitors in Type 2 Diabetes
A large-scale study suggests a common type 2 diabetes drug, glipizide, may increase cardiovascular risk compared to newer alternatives.