The CAVIAR trial found that alirocumab, in addition to statin therapy early after heart transplantation, safely lowered LDL-C but did not reduce coronary artery plaque progression after one year in patients with low baseline LDL...
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Early-Life Blood Pressure Management for Cardiac Health
This study found that higher life-course blood pressure, steeper increases, and greater cumulative burden are associated with lower myocardial perfusion at age seventy-seven, linking to higher MACE odds and fibrosis burden.
Hemodynamic and Anatomical Evaluation of HeartMate 3 in HFpEF
This study indicates that the HeartMate 3 in a left atrial to aortic configuration may relieve pulmonary congestion in some heart failure with preserved ejection fraction patients, contingent on careful pre-surgical anatomical...
Time-Restricted Eating Effects on Women with Overweight
This randomized crossover trial found that intended isocaloric time-restricted eating, whether early or late, did not improve insulin sensitivity or other cardiometabolic traits in women with overweight, despite shifting internal...
Drug Interventions for PFAS Excretion in Humans
A study suggests that medications like cholestyramine and colesevelam may significantly accelerate the elimination of persistent PFAS chemicals from the body, particularly PFOS, in highly exposed individuals.