This research investigates the impact of congenital heart disease on community engagement, neuropsychiatric conditions, and quality of life in adults with Down syndrome.
Most Recent Articles
Durable Remissions with GD2–CAR T Cells in Pediatric Neuroblastoma
This article presents the final results of a phase 1/2 clinical trial confirming that GD2-targeting CAR T cells induce durable remissions in children with high-risk neuroblastoma.
Integrating Drug-Target Predictions and EHR Data for Heart Failure Treatment Efficacy
This article details a novel framework leveraging electronic health records and drug-target predictions to enhance the accurate prediction of efficacy for repurposed heart failure therapies in clinical trials.
Microbiota Metabolite 2-Methylisocitrate Modulates 5-FU Chemotherapy Efficacy
This article investigates how a specific metabolite from the cancer-associated microbiota can significantly modulate the effectiveness of chemotherapy, presenting a promising new direction for cancer treatment strategies
Precision Medicine for Obesity: Genetic Subtypes and Their Distinct Risk Profiles
New genetic research reveals specific variants that uncouple obesity from cardiometabolic comorbidities, providing biological insights for precision medicine approaches.