This research introduces a conceptual framework of "brain–body states" that integrates cardiovascular and mental functions, offering new insights into the co-occurrence and development of related diseases.
Most Recent Articles
Tailored Factor IX-Albumin Fusions: Dictating Hemostasis and Distribution in Hemophilia B
This medical research explores how engineered factor IX with tailored collagen binding, when fused to albumin, dictates its in vivo distribution and functional half-life, offering new avenues for hemophilia B replacement therapy.
Body Composition from MRI: Beyond BMI for Cardiometabolic Risk
This study uses AI-derived body composition from MRI to identify key compartments associated with cardiometabolic outcomes, including diabetes and major adverse cardiovascular events.
Microbiome-Host Epigenome Interactions: Mechanisms and Health Implications
This review explores how the gut microbiome profoundly influences host epigenomic reprogramming, impacting human health and disease through various molecular mechanisms.
Targeting NAD+ in the Clinic: Strategies, Applications, and Challenges
This review explores emerging clinical strategies for targeting NAD+ to address aging and neurodegenerative diseases, discussing precursors and future research needs.