A Phase IIb clinical study shows that the novel antifungal drug olorofim achieved over 70% clinical improvement in patients with treatment-resistant disseminated Valley Fever.
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Coronary Intravascular Micro- and Nanoplastic Burden Across the Spectrum of Coronary Artery Disease
A clinical study reveals that micro- and nanoplastics are detected in 84% of heart attack patients and correlate strongly with smoking, air pollution, and systemic inflammation.
Novel Pharmacological Approaches to Myocardial Thickening: A Randomized Controlled Trial of Trientine
A yearlong trial reveals that trientine, a drug targeting copper metabolism, significantly reduces left ventricular mass and myocardial thickening in patients with hypertrophic cardiomyopathy.
Two-Decade Prospective Cohort Analysis of Neighborhood Disadvantage and Women’s Heart Health
A long-term study reveals that living in socioeconomically disadvantaged neighborhoods drives persistent cardiovascular health disparities and accelerates heart health declines in women approaching menopause.
Machine Learning Identification of Imminent Sudden Cardiac Arrest Warning Sign Combinations
Integrating warning symptom combinations with recurrent cardiovascular event tracking improves the prediction of out-of-hospital sudden cardiac arrest beyond traditional ejection fraction metrics.