Scientists have discovered that activating the glucocorticoid receptor in ovarian cancer cells drives immune evasion by attracting specialized suppressor cells that shield the tumor.
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Electron Transport Chain Modulation of Dendritic Cells in the Tumor Microenvironment
Scientists have discovered that mitochondrial complex I acts as a metabolic switch in dendritic cells, controlling their ability to activate T cells against viruses and tumors.
Characterizing Right Atrial Phenotypic Shifts and Tissue Scarring in Persistent Atrial Fibrillation
Advanced proteomic mapping reveals that persistent atrial fibrillation damages the right atrium just as severely as the left, indicating a critical need for bi-atrial clinical therapies.
Peptide-Mediated Trapping of Methylglyoxal to Prevent Neurodegenerative Complications After Myocardial InfarctionÂ
New research shows that heart attacks release a toxic molecule called methylglyoxal that travels to the brain, causing widespread neuroinflammation and blood-brain barrier degradation.
Molecular Biomarkers of Ventricular Remodeling in Advanced Heart Failure Patients
Scientists have discovered that restoring the muscle-specific protein PERM1 allows advanced heart failure patients to regain cardiac function by repairing cardiomyocyte energy production.