An immunotherapy checkpoint inhibitor significantly reduces the risk of disease recurrence in patients recovering from early-stage kidney cancer surgery.
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Oncogenic KRAS Activation of the cGAS-STING Axis as a Therapeutic Vulnerability in Pancreatic Cancer
Scientists have uncovered a major molecular vulnerability in pancreatic cancer cells, showing that oncogenic KRAS mutations can be exploited to trigger an inflammatory form of programmed cell death.
Restoring Cellular Energetics and Glomerular Filtration via Monoclonal ENPP1 Inhibition
A newly developed monoclonal antibody engineered to help heart tissue heal has been shown to successfully stimulate regeneration and reverse functional decline in damaged kidney tissues.
Clinical Efficacy of the Connect Me BP Digital Telemonitoring Service in Hypertension Management
A population-wide study reveals that home blood pressure telemonitoring significantly reduces long-term risks of stroke, heart attack, hospitalizations, and mortality in patients with hypertension.
Cardiac MRI Metrics of Subclinical Remodeling and Incident Cancer Risk in the MESA Cohort
A long-term study reveals that subtle, asymptomatic changes in heart structure and function detected on cardiac MRI are strongly associated with an increased risk of developing cancer years later.