In a 48-week, phase 2b, double-blind, randomized, placebo-controlled trial, the safety and efficacy of plozasiran, a hepatocyte-targeted APOC3 small interfering RNA, were evaluated in patients with mixed hyperlipidemia. The study...
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Computational Analysis of Pulmonary Vein Influence on Left Atrial Appendage Blood Flow and Thrombus Formation in Atrial Fibrillation
The study delves into the intricate relationship between left atrial appendage (LAA) morphology, blood flow patterns, and thrombus formation in atrial fibrillation (AF) patients, with a particular focus on the influence of...
The Role of Epigenetic Age Biomarkers in Mediating the Relationship Between LE8 Score and Cardiovascular Health Outcomes
In a study involving 5682 participants from the Framingham Heart Study, the relationship between Life’s Essential 8 (LE8) score, DNA methylation‐based epigenetic age biomarkers, and cardiovascular health was investigated. The LE8...
VISUALIZED: Incidence of Kidney Complications in Older Adults Following Hospitalization for Heart Failure: A Retrospective Cohort Study
Read further: Incidence of Kidney Complications in Older Adults Following Hospitalization for Heart Failure: A Retrospective Cohort Study
Incidence of Kidney Complications in Older Adults Following Hospitalization for Heart Failure: A Retrospective Cohort Study
In a retrospective cohort study of 85,298 Medicare beneficiaries hospitalized for heart failure (HF), it was found that 6% of individuals progressed to dialysis within one year after HF hospitalization. Additionally, 63% of the...