Article Impact Level: HIGH Data Quality: STRONG Summary of Frontiers in Medicine, 11. https://doi.org/10.3389/fmed.2024.1396962 Dr. Naomi D. L. Fisher et al.
Points
- The study examined blood pressure (BP) time-in-target range (TTR) as a key predictor of cardiovascular risk. It highlighted the limitations of conventional BP measurement methods in accurately assessing TTR.
- Utilizing continual monitoring, the research analyzed 2.3 million BP readings from 5,189 European home users, primarily male (82%) with a mean age of 55, using a cuffless BP monitor from Aktiia SA.
- Subjects were classified into risk-related TTR groups based on 15-day systolic BP (SBP) data, with a target range of 90–125 mmHg and at least six daytime readings; various measurement frequencies and durations were compared to the reference TTR.
- The study found that a one-week, 24-hour continual monitoring schedule was needed to achieve a classification accuracy of ≥90% in TTR assessment, especially for subjects with varying risk levels.
- The reference TTR categorized subjects into high-risk (63.0%), intermediate (19.0%), and low-risk (18.0%) groups, emphasizing the importance of continual cuffless BP monitoring in improving hypertension management and potentially revolutionizing BP monitoring practices.
Summary
The study focused on the significance of blood pressure (BP) time-in-target range (TTR) as a crucial predictor of cardiovascular risk and the limitations of conventional BP measurement methods in assessing TTR accurately. The research aimed to determine the optimal duration and frequency required for reliable TTR assessment in clinical settings by utilizing continual monitoring. This retrospective analysis involved 2.3 million BP readings from 5,189 European home users, with subjects having a mean age of 55 years and predominantly male (82%), using a cuffless BP monitor from Aktiia SA.
The study classified subjects into risk-related TTR groups based on 15-day systolic BP (SBP) data, with a target range of 90–125 mmHg and a minimum of six daytime readings. Various measurement frequencies and durations were compared to the reference TTR, with specific configurations resembling ambulatory and home BP monitoring selected for detailed analysis. The results indicated that a one-week, 24-hour continual monitoring schedule was necessary to achieve a classification accuracy of ≥90% in TTR assessment, particularly for subjects with varying levels of risk.
The reference TTR categorized subjects into high-risk (63.0%), intermediate (19.0%), and low-risk (18.0%) groups. The study highlighted the importance of continual cuffless BP monitoring in enabling practical and enhanced TTR assessment for hypertension management. The findings underscored the critical role of cuffless BP technologies in revolutionizing BP monitoring practices and hypertension management, offering potential advancements in assessing and controlling hypertension in clinical and research settings.
Link to the article: https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1396962/full
References Fisher, N. D. L., Almeida, T. P., Perruchoud, D., Shah, J., & Sola, J. (2024). Optimizing time-in-target-range assessment for blood pressure: Insights from a large-scale study with continual cuffless monitoring. Frontiers in Medicine, 11. https://doi.org/10.3389/fmed.2024.1396962
