Article Impact Level: HIGH Data Quality: STRONG Summary of European Heart Journal, ehad280. https://doi.org/10.1093/eurheartj/ehad280 Dr. Niels Scholte et al.
Points
- Home telemonitoring systems (TMS) in heart failure (HF) patients show promise in reducing all-cause mortality and HF-related hospitalizations.
- A comprehensive meta-analysis evaluated 65 non-invasive and 27 invasive hTMS studies involving 36,549 HF patients with an average follow-up of 11.5 months.
- Compared to standard of care, hTMS demonstrated a significant 16% reduction in all-cause mortality, a 19% reduction in first HF hospitalization, and a 15% reduction in total HF hospitalizations.
- The meta-analysis supports the advocacy for using hTMS in HF care, emphasizing the need for standardized and effective hTMS modalities.
- Future research should focus on standardizing hTMS methods to maximize their impact on reducing mortality and hospitalizations in HF patients.
Summary
This research paper aimed to evaluate the efficacy of home telemonitoring systems (TMS) in heart failure (HF) patients by conducting a comprehensive meta-analysis of relevant studies. The authors conducted a systematic literature search across four bibliographic databases, focusing on randomized trials and observational studies published between January 1996 and July 2022. The endpoints assessed were all-cause mortality, first HF hospitalization, and total HF hospitalizations.
The meta-analysis included 65 non-invasive hTMS studies and 27 invasive hTMS studies, enrolling 36,549 HF patients with an average follow-up period of 11.5 months. Comparing hTMS with standard of care showed a significant 16% reduction in all-cause mortality (pooled odds ratio: 0.84, 95% confidence interval: 0.77-0.93, I2: 24%). Additionally, a significant 19% reduction in first HF hospitalization (OR: 0.81, 95% CI: 0.74-0.88, I2: 22%) and a 15% reduction in total HF hospitalizations (pooled incidence rate ratio: 0.85, 95% CI: 0.76-0.96, I2: 70%) were observed in patients using hTMS compared to standard of care.
In conclusion, the findings of this meta-analysis provide strong evidence supporting the use of TMS in HF patients to reduce all-cause mortality and HF-related hospitalizations. However, the methods of hTMS varied across the studies included in the analysis. Therefore, future research should focus on standardizing effective hTMS modalities to enhance their impact on HF care.
Link to the article: https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehad280/7167125
References Scholte, N. T. B., Gürgöze, M. T., Aydin, D., Theuns, D. A. M. J., Manintveld, O. C., Ronner, E., Boersma, E., De Boer, R. A., Van Der Boon, R. M. A., & Brugts, J. J. (2023). Telemonitoring for heart failure: A meta-analysis. European Heart Journal, ehad280. https://doi.org/10.1093/eurheartj/ehad280
