Article Impact Level: HIGH Data Quality: STRONG Summary of JAMA Network Open, 7(5), e2413453. https://doi.org/10.1001/jamanetworkopen.2024.13453 Dr. Adam Viktorisson et al.
Points
- The longitudinal cohort study within the INTERGENE project explored the relationship between different types of physical activity and stroke incidence, along with post-stroke outcomes such as death or dependency on daily activities.
- The study included 3,614 individuals from western Sweden, aged 24 to 77, examined between 2001 and 2004, with some re-examined from 2014 to 2016. Participants self-reported their physical activity levels in four domains: leisure time, work, transportation, and household activities, with additional pedometer data for some.
- Higher levels of leisure time and transport physical activities were significantly correlated with reduced stroke risk. Intermediate and high levels of leisure time physical activity and intermediate levels of transport physical activity were associated with lower stroke incidences compared to low activity levels.
- High levels of leisure time physical activity significantly reduced the risk of death or ADL dependency post-stroke, indicating a protective effect on recovery outcomes.
- The study highlights the importance of integrating specific physical activity recommendations into public health policies to mitigate stroke risks and improve recovery outcomes, emphasizing the role of lifestyle factors in stroke prevention and post-stroke care.
Summary
In a longitudinal cohort study conducted within the Interplay Between Genetic Susceptibility and External Factors (INTERGENE) project, researchers explored the association between different types of physical activity and stroke incidence, along with post-stroke outcomes such as death or dependency in activities of daily living (ADL) three months following the event. The study encompassed a diverse group of 3,614 individuals from western Sweden, aged between 24 to 77 years, who were initially examined between 2001 and 2004, with a subset re-examined from 2014 to 2016. Over a median follow-up period of 20 years, participants self-reported their physical activity levels across four domains: leisure time, work, transportation, and household activities, with additional data on steps taken over six days collected via a sealed pedometer for some.
The findings indicated that higher levels of leisure time and transport physical activities significantly correlated with reduced stroke risk. Specifically, intermediate (adjusted hazard ratio [aHR], 0.54; 95% CI, 0.38-0.77) and high (aHR, 0.47; 95% CI, 0.31-0.73) levels of leisure time physical activity, as well as intermediate levels of transport physical activity (aHR, 0.69; 95% CI, 0.52-0.93), were associated with lower stroke incidences compared to low activity levels. Furthermore, high levels of leisure time physical activity significantly reduced the risk of death or ADL dependency post-stroke (adjusted odds ratio, 0.34; 95% CI, 0.16-0.71). Work and household physical activities did not significantly correlate with stroke incidence or outcomes.
The study underscores the protective effects of leisure and transport-related physical activities against stroke and subsequent death or disability. These findings highlight the potential for integrating specific physical activity recommendations into public health policies to mitigate stroke risks and improve recovery outcomes, emphasizing the importance of lifestyle factors in stroke prevention and post-stroke care.
Link to the article: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2819140
References Viktorisson, A., Palstam, A., Nyberg, F., Berg, C., Lissner, L., & Sunnerhagen, K. S. (2024). Domain-Specific Physical Activity and Stroke in Sweden. JAMA Network Open, 7(5), e2413453. https://doi.org/10.1001/jamanetworkopen.2024.13453
