Cardiology Research

Effects of a Healthy Diet and Exercise on Cardiovascular Health: The DECIDE-Diet Trial

Article Impact Level: HIGH
Data Quality: STRONG
 Summary of Circulation, 146(4), 303–315. https://doi.org/10.1161/CIRCULATIONAHA.122.059045
Dr. Yanfang Wang et al

Points

  • The DECIDE-Diet trial set out to examine individuals with mild hypertension to evaluate the benefits of following a Chinese heart-healthy diet.
  • The study (n = 265, mean age = 57 years old) gathered individuals with a systolic blood pressure of 130-159 mmHg. Primary outcomes included systolic blood pressure, with diastolic blood pressure measured as a secondary outcome.
  • Results showed a 14.7 mmHg decrease in the primary outcome for the Chinese heart-healthy diet group compared to baseline; this stands against the 4.8 mmHg decrease in the control group. Secondary outcomes also showed a 6.3 mmHg decrease in the heart-healthy group compared to baseline vs. a 2.6 mmHg decrease in the control.
  • Overall, the Chinese heart-healthy diet was found to be effective at lowering systolic blood pressure among Chinese individuals with mild hypertension.

Summary

In an attempt to evaluate the advantages of following a Chinese heart-healthy diet compared to a control, the DECIDE-Diet trial set out to examine Chinese individuals with mild hypertension.

The randomized, parallel study considered Chinese individuals with mild hypertension and compared them with a control (n = 135 vs. n = 130, respectively; mean age = 57 years old; 52% female vs. 48% male). Inclusion criteria included Chinese individuals between 25-75 years of age and with a systolic blood pressure of 130-159 mmHg. The diet enacted upon the mild hypertension group was composed of a reduced energy intake from fats and an increased energy intake from both proteins and carbohydrates compared to the control; meanwhile, sodium intake was reduced from 6,000 to 3,000 mg/day. A 28-day follow-up period was enacted. Primary outcomes were recorded in systolic blood pressure, with diastolic blood pressure recorded as part of secondary outcomes.

Principal results showed a 14.7 mmHg decrease in the Chinese heart-healthy diet group compared to baseline, while a 4.8 mmHg decrease was observed in the control (p < 0.001). Meanwhile, no treatment interaction was observed with respect to differences in regional cuisine (pinteraction = 0.17). Secondary findings revealed a 6.3 mmHg decrease in diastolic blood pressure in the Chinese heart-healthy diet group compared to baseline; this stood in comparison to a 2.6 mmHg decrease in the control (p < 0.001). Ratings in food preferences across both groups stayed at 0.1 (p = 0.56) while costs remained similar.

In conclusion, a Chinese heart-healthy diet was shown to be effective at lowering systolic blood pressure among Chinese individuals compared to a control diet, with significant reductions in both primary and secondary outcomes over the 28-day trial period.

Link to the article: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.059045

References

Wang, Y., Feng, L., Zeng, G., Zhu, H., Sun, J., Gao, P., Yuan, J., Lan, X., Li, S., Zhao, Y., Chen, X., Dong, H., Chen, S., Li, Z., Zhu, Y., Li, M., Li, X., Yang, Z., Li, H., … Qiu, S. (2022). Effects of cuisine-based Chinese heart-healthy diet in lowering blood pressure among adults in china: Multicenter, single-blind, randomized, parallel controlled feeding trial. Circulation, 146(4), 303–315. https://doi.org/10.1161/CIRCULATIONAHA.122.059045

About the author

Hippocrates Briefs Team