Article Impact Level: HIGH Data Quality: STRONG Summary of Journal of Stroke, 26(3), 391–402. https://doi.org/10.5853/jos.2024.01543 Dr. Andrew Smyth et al.
Points
- The study analyzed the association between cold beverage intake and stroke risk using data from the INTERSTROKE study, involving 13,462 stroke cases and 13,488 controls.
- Carbonated beverage consumption was linked to an increased risk of ischemic stroke (OR 2.39) and intracerebral hemorrhage (ICH) (OR 1.58 for daily intake).
- Fruit juice intake was associated with an increased risk of ICH, particularly for those consuming it daily or twice daily, but showed no association with ischemic stroke.
- High water intake (more than seven cups per day) was linked to reduced odds of ischemic stroke (OR 0.82) but had no significant relationship with ICH.
- The findings suggest reducing carbonated and fruit juice consumption while increasing water intake to lower stroke risk, though regional variability should be considered.
Summary
This study examined the association between cold beverage intake and stroke risk using data from the INTERSTROKE study, an international case-control study of first-time stroke patients. The analysis included 13,462 stroke cases and 13,488 controls, with a mean age of 61.7 years; 59.6% of participants were male. Beverage intake was assessed using food frequency questionnaires, and associations were analyzed using multivariable conditional logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for both ischemic stroke and intracerebral hemorrhage (ICH).
Results showed a significant association between carbonated beverage consumption and increased risk of ischemic stroke (OR 2.39, 95% CI 1.64–3.49). Specifically, consuming carbonated drinks once daily was linked to higher odds of ICH (OR 1.58, 95% CI 1.23–2.03). For fruit juices or drinks, no association with ischemic stroke was observed, but an increased risk of ICH was found for those consuming these drinks once daily (OR 1.37, 95% CI 1.08–1.75) or twice daily (OR 3.18, 95% CI 1.69–5.97). High water intake, defined as more than seven cups per day, was associated with reduced odds of ischemic stroke (OR 0.82, 95% CI 0.68–0.99) but showed no significant relationship with ICH.
Regional differences in these associations were noted, including increased stroke risk linked to carbonated beverages in specific regions and variable associations for fruit juice consumption and stroke type. These findings suggest that reducing carbonated beverage and fruit juice consumption while increasing water intake may help lower the risk of stroke, particularly ischemic stroke. However, regional variability should be considered in dietary recommendations.
Link to the article: https://j-stroke.org/journal/view.php?doi=10.5853/jos.2024.01543
References Smyth, A., Hankey, G. J., Damasceno, A., Iversen, H. K., Oveisgharan, S., Alhussain, F., Langhorne, P., Xavier, D., Jaramillo, P. L., Oguz, A., McDermott, C., Czlonkowska, A., Lanas, F., Ryglewicz, D., Reddin, C., Wang, X., Rosengren, A., Yusuf, S., & O’Donnell, M. (2024). Carbonated beverage, fruit drink, and water consumption and risk of acute stroke: The interstroke case-control study. Journal of Stroke, 26(3), 391–402. https://doi.org/10.5853/jos.2024.01543
