Article Impact Level: HIGH Data Quality: STRONG Summary of Scientific Reports, 14(1), 21063. https://doi.org/10.1038/s41598-024-71426-y Dr. Bo Wang et al.
Points
- The study investigated the relationship between coffee and tea consumption and the risk of dementia in hypertensive individuals using data from 453,913 participants in the UK Biobank.
- A J-shaped association was found for coffee, and a U-shaped association for tea, with 0.5 to 1 cup of coffee and 4 to 5 cups per day linked to the lowest dementia risk in hypertensive individuals.
- Hypertensive patients in the highest coffee consumption group had a 22% reduced risk of dementia, while those consuming 4 to 5 cups of tea daily had a 33% lower risk.
- The protective associations of caffeine consumption were more pronounced in hypertensive individuals compared to non-hypertensive participants.
- The study suggests that moderate coffee and tea intake may offer neuroprotective benefits for hypertensive patients, but further research is needed to confirm these findings and explore the mechanisms involved.
Summary
This study aimed to investigate the association between coffee and tea consumption and the risk of dementia in hypertensive individuals. Using data from 453,913 participants in the UK Biobank, researchers applied Cox proportional hazard modeling to explore the relationship between daily caffeine intake and the risk of all-cause dementia, including vascular dementia. The study found a J-shaped association between coffee consumption and dementia risk and a U-shaped relationship for tea consumption. Specifically, hypertensive individuals consuming 0.5 to 1 cup of coffee or 4 to 5 cups of tea daily exhibited the lowest risk of developing dementia.
The analysis revealed that hypertensive patients in the highest coffee consumption group had a 22% reduced risk of dementia compared to those who did not consume coffee. A U-shaped association was also observed with tea consumption, with hypertensive participants who consumed moderate amounts of tea showing a significant decrease in dementia risk. For example, those drinking 4 to 5 cups of tea daily had a 33% lower risk of developing dementia. These associations were more pronounced in hypertensive patients than in non-hypertensive individuals, suggesting that caffeine intake might have a more substantial protective effect in those with hypertension.
The study concluded that moderate coffee and tea consumption is associated with a lower risk of dementia in hypertensive patients, supporting the potential neuroprotective benefits of caffeine. These findings could have significant implications for public health, particularly in the management of dementia risk among hypertensive populations. However, further research is needed to explore these associations’ underlying mechanisms and confirm these results in other populations.
Link to the article: https://www.nature.com/articles/s41598-024-71426-y
References Wang, B., Ma, T., Yang, L., He, S., Li, J., & Sun, X. (2024). Association between coffee and tea consumption and the risk of dementia in individuals with hypertension: A prospective cohort study. Scientific Reports, 14(1), 21063. https://doi.org/10.1038/s41598-024-71426-y
