Cardiology Research

Cardiovascular Health Scores as Predictors of Acute Kidney Injury in Noncardiac Surgery

Article Impact Level: HIGH
Data Quality: STRONG
Summary of Clinical Cardiology, clc.24159. https://doi.org/10.1002/clc.24159
Dr. Jin-Qiu Li et al.

Points

  • The research examined the link between Cardiovascular Health Scores (CHS) and perioperative Acute Kidney Injury (AKI) in 2,783 noncardiac surgery patients.
  • Participants with CHS scores of 10 or higher had a 57% lower risk of AKI than those with scores of 7 or lower, with a stronger effect observed in men.
  • Non-smokers, regular exercisers, and individuals with normal blood pressure exhibited reduced AKI risk, emphasizing the importance of lifestyle factors.
  • The study underscores a significant inverse relationship between CHS and AKI risk, offering potential insights for AKI prevention and treatment.
  • Future research is needed to explore the long-term impact of maintaining optimal cardiovascular health on AKI risk, extending the findings to a broader context.

Summary

In this research study, the relationship between Cardiovascular Health Scores (CHS) and the occurrence of perioperative Acute Kidney Injury (AKI) was investigated, shedding light on a previously unexplored connection. The study involved 2,783 participants who underwent general anesthesia during noncardiac surgeries between 2016 and 2020, drawn from the Kailuan study cohort. Logistic regression analysis was employed to calculate odds ratios (ORs) and 95% confidence intervals (CIs) to assess the impact of CHS on AKI risk.

Among the 2,783 participants, 187 were diagnosed with perioperative AKI. The findings revealed a noteworthy inverse relationship between CHS scores and the risk of AKI. Specifically, participants with CHS scores of 10 or higher exhibited a 57% lower risk of AKI (OR = 0.43, 95% CI = 0.23, 0.79) than those with CHS scores of 7 or lower. This association was particularly pronounced in men (OR = 0.39, 95% CI: 0.20, 0.76). Additionally, individuals who were non-smokers, engaged in regular exercise, and maintained normal blood pressure exhibited reduced AKI risk, with corresponding ORs (95% CIs) of 0.66 (0.47, 0.91), 0.73 (0.60, 0.92), and 0.46 (0.28, 0.75), respectively.

In conclusion, this study highlights a strong association between CHS and the risk of perioperative AKI, indicating that higher CHS scores are associated with a reduced risk of AKI. The findings suggest that efforts to achieve and maintain an ideal CHS may have potential implications for AKI prevention and treatment. However, further research is warranted to explore the long-term effects of maintaining optimal cardiovascular health on the risk of AKI in a broader context.

Link to the article: https://onlinelibrary.wiley.com/doi/full/10.1002/clc.24159

References

Li, J., An, Y., Wang, T., Guo, P., Chen, S., Liu, B., & Liu, H. (2023). Relationship between ideal cardiovascular health score and perioperative acute kidney injury: A caseā€control study. Clinical Cardiology, clc.24159. https://doi.org/10.1002/clc.24159

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